Faculty

Mei'ai Lin

Lecturer

PHD

Research Fields
 Biomedical optical imaging, droplet microfluidics and single cell/exosomes analysis.
Bio

Dr. Lin received her doctorate degree in Biomedical engineering from Shandong University in 2019 and was awarded Outstanding Postgraduate Scholarship and Academic Achievement Prize.

Dr. Lin also received the financial support (the first prize) from program for Outstanding PhD candidate of Shandong University. 

Dr. Lin has published 2 academic journal papers (JCR-Q1), 2 peer-reviewed conference papers (EI) and 2 Chinese authorized patents. She serves as reviewer for the journal of Biomedical Optics Express.

Contact
E-mail: meiailin@stu.edu.cn
Personal Website

Education

2013.09-2019.06Biomedical Engineering, Shandong University, PhD student

2009.09-2013.06Biomedical Engineering, Shandong University, undergraduate


Work Experience

2019.07 —:Department of Biomedical Engineering, Shantou University


Research

Biomedical optical imaging and droplet microfluidics


Current Projects:

1.  Li Ka Shing Foundation Cross-Disciplinary Research Grant “Application of exosome detection technology based on integrated microfluidic in stroke diagnosis”, 2020-2023

2.  Guangdong Basic and Applied Basic Foundation- Youth program “Exosomes tracking based on light scattering imaging for analysis of neurons injury”, 2020-2023

3.  Guangdong Basic and Applied Basic Foundation- General program “Functionalized black phosphorus quantum dots based light scattering imaging and its application in fast detection and dynamic analysis of exosomes”, 2021-2024



Publications

1. Lin M.A.,Liu T., Zheng Y.X. and Ma X.Y.* "Dynamic light scattering microscopy sensing mitochondria dynamics for label-free detection of triple-negative breast cancer enhanced by deep learning," Biomedical Optics Express 14(10), 5048-5059 (2023) https://doi.org/10.1364/BOE.502083 

2. Lin M.A., Liu T.; Liu Y.Q.; Lin Z.Q.; Chen J.L.; Song J.; Qiu Y.Y. and Zhou B.Q.*, “Three-Dimensional Printing Enabled Droplet Microfluidic Device for Real-Time Monitoring of Single-Cell Viability and Blebbing Activity” [J]. Micromachines 2023,14,1521. https://doi.org/10.3390/mi14081521 

3. M. Lin, J. Huang, J. Fu, Y. Sun and Q. Fang, "A VR-Based Motor Imagery Training System with EMG-Based Real-Time Feedback for Post-Stroke Rehabilitation," IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2022, doi: 10.1109/TNSRE.2022.3210258. 

4. Zhou B.Q, Liu J., Lin M.A.*, Zhu J.*, Chen W.R.*. "Recent advances in immunotherapy, immunoadjuvant, and nanomaterial-based combination immunotherapy," Coordination Chemistry Reviews. 442(2021). 

5. Lin M.A., Liu Q., Liu C., Qiao X., Shao C.S. and Su X.T.*, Label-free light-sheet microfluidic cytometry for the automatic identification of senescent cells[J]. Biomedical Optics Express, 2018, 9(4): 1692-1703. DOI: 10.1364/BOE.7.005170 

6. Lin M.A., Qiao X., Liu Q., Shao C.S. and Su X.T.*, Light-sheet-based 2D light scattering cytometry for label-free characterization of senescent cells[J]. Biomedical Optics Express, 2016, 7(12): 5170-5181. 

7. Lin, Z., Zhang, W., Liu, T., Luo, S., Wu, Y., Liu, Y., ... & Lin, M. 3D printed microfluidics-based droplet generation for single cell encapsulation and optical imaging. Proceedings of SPIE (Vol. 12320)., 2022.12   doi: 10.1117/12.2644130  

8. Liu, T., Ma, X., Luo, S., Zhang, W., Lin, Z., & Lin, M. Dynamic light scattering imaging for cell detection of HER-2 positive and triple negative breast cancer. Proceedings of SPIE 2022, December  doi: 10.1117/12.2644061 

9. Ting Liu, Xiaohang Zhou, Zejie Lin, Jiale Chen and Meiai Lin*, “3D-printing based microfluidic device for fast light scattering imaging of single cells” Proceedings of SPIE, 2021. doi.org/10.1117/12.2601335 

10. Jianli Huang, Meiai Lin*, Jianming Fu, Ya Sun, Qiang Fang , “An Immersive Motor Imagery Training System for Post-Stroke Rehabilitation Combining VR and EMG-based Real-Time Feedback,” Annu Int Conf IEEE Eng Med Biol Soc. 2021-12 

11. Lin M.A*, Huang J. L., Hong S., "Volume scanning-based light scattering microscopy for fast 3D localization of single particles," Proceedings of SPIE, 2020. doi: 10.1117/12.2579209 

12. Lin M.A., Zhang S.Y., Liu Q., Shao C.S. and Su X.T.*, Label-free analysis of senescent cells by light sheet microfluidic cytometry with a disposable hydrodynamic focusing unit [C]. Proceedings of SPIE, 2019. doi: 10.1117/12.2534145 

13. Lin M.A. and Su X.T.*, 2D light scattering label-free cytometry using light-sheet illumination[C]. Proceedings of SPIE, 2016. 


Patents

1. Invention Patent: Xuantao Su, Meiai Lin, Qiao Liu, Xu Qiao, “ A label free cell detection device and method based on light-sheet illumination”, ZL201610890421.5.

2. Invention Patent: Xuantao Su, Meiai Lin, “ A label free microfluidic cytometry and method based on light -sheet illumination and sheath flow technology”, ZL201810183035.1.

3. Utility Model Patent: Meiai Lin, Zequan Lin, Shentao Liao, Wencong Zhang, Ting Liu, “A microfluidic sheath flow apparatus”, ZL202221382785.X

4. Invention Patent: Meiai Lin, Ting Liu, Yeqian Liu, Yixiong Zheng, “Photothermal effect based interference scattering microscopy and imaging method”, 202310968409.1


Teaching

1.Undergraduate Course

[BME2202A]Introduction to Biomechanics

[BME3104A]Quantitative Cell Biology

2.Teaching reform program:<Introduction to Biomechanics>-Study of synchronous vs. asynchronous hybrid teaching. (School-level project) 2021-2022

Teaching reform paperRamo, N.L., Lin, M., Hald, E.S. Huang-Saad,. "Synchronous vs. Asynchronous vs. Blended Remote Delivery of Introduction to Biomechanics Course." Biomedical Engineering Education (2020 August). https://doi.org/10.1007/s43683-020-00009-w





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