Recently, the international authoritative journal coordination chemistry reviews (top journal of Chinese Academy of Sciences zone 1, if: 15.367) received the review paper "recent advances in immunology, immunoadvance, and nanomaterial based combination Immunology" from the Department of Biomedical Engineering, School of technology, Shantou Universit (the latest research progress of immunotherapy, immunoadjuvant, combined immunotherapy based on nanomaterials). The first unit of this paper is Shantou University, and the first author is Zhou Benqing, associate professor of Biomedical Engineering Department of Shantou University.

Cancer immunotherapy has become the fourth major cancer treatment method in addition to chemotherapy, radiotherapy and surgery, which is the focus and key direction of cancer treatment research.There are many kinds of cancer immunotherapy, which can be divided into vaccine immunotherapy, cytokine immunotherapy, checkpoint blocking immunotherapy, adoptive cell transfer immunotherapy and small molecule immunotherapy.These treatments and their limitations are described in detail in this review. In addition, since many immunotherapies rely on immune adjuvants and nano platforms, this paper also summarizes different types of immune adjuvants for cancer immunotherapy, including toll like receptor agonists, plant-derived immune adjuvants, aluminum salt adjuvants and other immune adjuvants. Finally, the combination of immunotherapy based on nanomaterials with chemotherapy, phototherapy, radiotherapy and other therapies is introduced in detail.